|
Current Concepts & Treatment: Non-Invasive Breast
Cancer
N. Craig
Brackett, III, MD, FACS
Angela M. Mislowsky, MD
Ductal Carcinoma in Situ (DCIS)
of the breast is a heterogeneous group of lesions with
diverse malignant potential and is associated with a
range of controversial treatment options. DCIS is, by
definition, non-invasive or pre-invasive breast cancer
and is classified as a Tis lesion in our current staging
system (Stage 0). DCIS now constitutes up to 20% of all
newly diagnosed breast cancers and according to 2010
American Cancer Society data, over 54,000 cases were
diagnosed last year. It is the most rapidly growing
subgroup within the breast cancer family. Advances in
breast imaging and emphasis placed on screening programs
have lead to this increase in diagnosis.
The diagnosis of DCIS is
made by screening mammography 90% of the time.
Mammographically seen microcalcifications are considered
the hallmark of this disease. Stereotactic core needle
biopsy (SCNB) is the preferred technique in diagnosing
this disorder. SCNB is an accurate, minimally invasive,
outpatient procedure that takes 20-30 minutes to
perform. At our women’s imaging centers, we have done
over 2,000 of these biopsies.
Once the diagnosis is made
by our pathologists, the patient is informed of her
diagnosis and each treatment option is discussed with
her in detail. The goal of treatment is to cure the
patient of a noninvasive cancer, even if it means having
to perform a mastectomy. However, less than 25% of women
with DCIS will need a mastectomy, leaving 75% of
patients with the possibility of breast conservation as
their option. This is where the controversy over
treatment options comes into play.
Breast conservation
surgery (BCS) is defined as lumpectomy or tumor excision
with uninvolved margins, with or without post-operative
whole breast irradiation (XRT). We know that mastectomy
is 99% effective in treating this disease so BCS needs
to approach this success rate in order to be offered as
a treatment option.
There are clinical trials
that address the use of breast conservation in the
treatment of DCIS. These trials have shown that
all patients benefited from whole breast irradiation
with a 50% reduction in breast cancer recurrences.
Despite its benefits, post-operative XRT is not without
complications including fibrosis, decreased sensitivity
of follow up mammograms, inability to use XRT for cancer
recurrences, and it may cause difficulties in future
surgeries if they are needed. Radiation centers are also
not always accessible to the patient and it is expensive
and time consuming.
The development of
accelerated partial breast irradiation (APBI) given
through a radiation catheter placed in the office is
being evaluated for use in the treatment of DCIS.
Currently, APBI is showing excellent local recurrence
rates and cosmetic outcomes in early stage breast
cancers. It is hopeful that APBI will be less time
consuming, less expensive, just as effective as whole
breast XRT, and with a much lower complication rate.
Clinical trials have
compared BCS with post-op radiation therapy with and
without the addition of Tamoxifen. The addition of
Tamoxifen statistically decreased the amount of invasive
recurrences. We currently treat our patients with DCIS
with 20 mg of Tamoxifen once a day for five years.
In our practice, treatment
decisions are based on a variety of parameters including
tumor size, margin width, nuclear grade, and age of the
patient. These parameters form the basis of the Van Nuys
Prognostic Index (VNPI); a scoring system for DCIS
developed by Dr. Mel Silverstein and colleagues that is
a useful guide in the decision making process. There are
basically four treatment options for DCIS of the breast:
lumpectomy, lumpectomy with accelerated partial breast
irradiation, lumpectomy with whole breast irradiation,
and mastectomy. In addition to the VNPI, cancer
pathology, mammography, and close communication between
the surgeon, radiologist, and pathologist are key
components to proper decision making. Together, these
factors allow us to better estimate the risk of
recurrence and the benefit of additional treatment, in
particular, the use of XRT and Tamoxifen.
DCIS is a non-invasive form
of breast cancer that does not usually spread to lymph
nodes so sentinel lymph node dissection is not generally
indicated. However, situations may arise that make its
ease of use applicable: large upper, outer quadrant
lesions of high grade necrosis, DCIS with microinvasion,
DCIS with a mass, and in patients who are undergoing a
mastectomy. Furthermore, if invasive cancer is found in
the initial lumpectomy specimen, one can usually go back
and perform SLNB at a later time.
The use of cytotoxic or
systemic chemotherapy is not required in the treatment
of DCIS. As mentioned before, Tamoxifen, taken 20 mg a
day for five years, plays a role in reducing invasive
recurrences. In the future, molecular studies will show
which lesions have a high propensity of local recurrence
and microinvasion. This will help us determine even more
accurate treatment options.
It is generally thought
that the likelihood of developing an invasive cancer in
the conservatively treated breast is approximately 1% or
less per year following initial diagnosis and treatment.
This is one reason why organized and timely follow up is
important in these patients.
The treatment of
recurrences that develop in the treated breast will
depend on the initial treatment employed. If the patient
initially had lumpectomy alone, then she is a possible
candidate for re-excision and radiation. However, many
recurrences are treated with mastectomy as most patients
have usually received postoperative XRT in their initial
treatment. Any invasive recurrence is treated as you
normally would based on the stage of the cancer.
In summary, DCIS is a
curable, non-invasive form of breast cancer with 97%
survival at 15 years. The keys to achieving a cure are
proper margin determination, proper pathological
classification, and communication between the surgeon,
pathologist, and radiologist. There are a wide variety
of treatment options. These include: lumpectomy,
lumpectomy and radiation, and mastectomy.
Coastal Carolina Breast
Center is the area’s only practice dedicated solely to
breast health. In addition to being accredited by NAPBC,
it is recognized as a Center of Excellence. Breast
specialist, N. Craig Brackett, III, MD, FACS, joined in
practice by Angela M. Mislowsky, MD, has treated an
estimated 25,000 patients during the last fifteen years.
Their offices are located at the Imaging Center at
Waccamaw Medical Park in Murrells Inlet and the Frances
B. Ford Cancer Center in Georgetown, South Carolina.
Physician referrals are not required. For more
information, or to make an appointment, call (843)
651-3308.
Questions Frequently Asked about Breast Enhancement
Kimberley B.C. Goh, M.D.
Am I a candidate for breast enhancement?
If you have never had
much breast development or if you have lost some volume
with pregnancy, weight loss or menopause, you might be a
candidate for enhancement.
How do I know if I am a candidate for a breast
enlargement or if I need a lift with the implant?
If there is significant
sagging or the breasts have an unusual shape they may be
better corrected with an implant and a lift. Just
simply placing an implant into the breast if the breast
is very saggy or a different shape is not enough.
What are the risks involved and what things should I
consider?
There are risks and
future costs to consider before you decide to have
breast enhancement surgery. Implants are mechanical
devices and will not last forever. Just like an
artificial hip, knee or heart valve, they eventually
wear out. You likely will need surgery again on your
breasts, either to remove or replace the implants. The
implants used for augmentation are saline or silicone
gel in a silicone plastic envelope.
If the saline implant
leaks, it will go flat and the saline absorbed by your
body, if the silicone leaks it is usually trapped within
the scar around your implant. Silicone that has leaked
will need to be removed with surgery. Saline implants
that have leaked also need removal of the now empty
envelope.
Your mammogram will be
affected by the implant. Both silicone and saline
filled breast implants will affect your mammogram to a
small degree. Extra views will be necessary to make a
more complete examination of your breast
Another possible
complications of breast implants is that your body may
form a tight scar or capsular contracture around them.
This is true for either silicone filled or saline filled
implants. It may be necessary to re-operate to release
the scar and make the breast soft again, and
unfortunately it’s possible that even after a surgical
release that the tight scar could recur.
What are the advantages of silicone implants versus
saline and how do I choose?
The silicone filled
breast implant has an advantage over the saline filled
breast implant in its texture and appearance. If the
original breast is small and the implant is large, or
the tissue covering the implant is very thin the
silicone may give a better appearance and more natural
feel. Sometimes the saline filled breast implant will
have a visible edge with rippling. If you are going
from a very small breast to a large breast, are very
thin or are placing the implant on top of the muscle
with very little breast tissue or fat covering it, then
silicone may be a good choice if the texture and lack of
rippling is important to you. For example builders or
fitness contestants may do better with a silicone
implant over the muscle. However, if you are increasing
your size a modest amount or if you have a moderate
amount of breast or soft tissue to cover it then a
saline implant may work very well.
To place a silicone
implant there is a longer scar, the implants themselves
costs more, and it is more expensive to remove them than
for a saline filled implant. MRI may be necessary of
the silicone implants in the future, and it may not be
covered by your insurance carrier. If the implant has
leaked, then silicone will be outside of the implant
coating the scar around the implant, or perhaps even
leaked beyond the scar into your breast tissue. To
remove the silicone you will also need to remove the
capsule around the implant, so this involves more
surgery than needed to remove a saline implant.
Are silicone implants safe?
The silicone implant
information collected over a fifteen year prospective
study and presented to the FDA revealed no increased
incidence of immune disorders with silicone implants
(i.e. Rheumatoid arthritis, scleroderma, lupus, etc.)
Who should do my
surgery and where should I have it?
There are many things you
should consider if you want breast enhancement. It is
important to discuss the operation and other details
with your surgeon. Your surgeon should be chosen with
care. A surgeon who is board certified by the American
Board of Plastic Surgery has had at least five to seven
years of intensive post-graduate training. This
training includes academic instruction and rigorous
supervised hands on surgical training. The training
involves not only the surgery of the implants and lifts,
but also teaches the skills to choose patients and avoid
and address complications. There are many people
performing cosmetic procedures with little or no formal
training. It is in your best interest to check on the
experience and qualifications of the physician you
choose to perform your surgical procedure. A surgical
suite in a physician’s office can allow for more privacy
and decrease costs. If you have your surgery done in a
surgical center, make sure that is certified by the
American Association for the Accreditation of Ambulatory
Surgical Facilities, or other nationally recognized
certifying agencies. Breast enhancement can enhance your
body and make you more confident, but it is surgery.
Understand what it can do and what to expect in the
future.
Kimberley B.C. Goh, M.D.
Grand Strand Plastic and
Reconstructive Surgery Center, P.A.
4610 Oleander Drive Suite
101
Myrtle Beach, SC 29577
(843) 497-2227
gsprs@sc.rr.com
kimberleygohmd.com
Gritty, Itchy Eyes Or Blurred Vision?
It Could be “Dry Eye Disease”.
Dr Thomas Weshefsky
How do your eyes feel?
·
Do they hurt?
·
Do they feel dry, scratchy or gritty?
·
Do they have a burning sensation?
·
Do they have a foreign body sensation?
·
Are they itchy?
·
Are they sensitive to light?
·
Are tears running down your cheeks?
·
Do they become increasingly more tired during the day?
·
Does your vision fluctuate?
·
Do you experience irritation from smoke, wind, or air
movement?
·
Is your vision blurred?
·
Are they red?
·
Do you have problems wearing contact lenses?
If you answered yes to one or more of these questions
then you are likely one of the 30 million Americans who
suffer from “dry eye”.
You may have tried over the counter eyedrops only to
discover that they provided little to no relief.
Perhaps you have even discussed your symptoms with your
eye doctor and he or she gave you a bottle of artificial
tears to try.
Did it work? It probably made you feel a bit better for
a few minutes but did it really work? Most likely, it
did not and you just resigned yourself to “learning to
live with it” because it is just part of the aging
process.
Unfortunately, this situation is all too common.
According to a 2008 Gallup poll, the symptoms of dry eye
are either the primary or secondary reason for nearly
half of all visits to an eye doctor. The problem is
that nine out of ten people who experience these
symptoms have none of the classic clinical signs of dry
eye. That means that when the doctor examines those
people their eyes appear perfectly healthy and the
condition is not judged to be serious. However, the
patient still feels significant pain.
Doctors in general and eye doctors in particular are
trained to connect patient symptoms with their clinical
signs. Once this connection is made and the diagnosis
is confirmed, treatment can begin. Most of the time,
this system of patient care works exceedingly well.
However, 90% of dry eye sufferers have no clinical
signs, and as a result, this connection cannot be made
and the condition is often judged to be not significant
enough to warrant any major treatment.
Although the symptoms of dry eye have plagued mankind
from the beginning, dry eye was not officially
recognized as an eye condition until 1994 when a team of
doctors from the National Eye Institute defined it as a
“disorder”.
It wasn’t until 2007, that dry eye was finally
classified as a “disease”. This occurred
when a large international team of leading experts
released the results of a three year study called the
dry eye Workshop (DEWS) report. Their study developed a
very precise definition of dry eye disease as well as
guidelines for its diagnosis, classification and
treatment. They recognized that dry eye cannot be
effectively treated using clinical signs alone. Doctors
must also track patient symptoms to effectively manage
dry eye.
The good news is that you do not have to live with the
pain anymore. When a careful patient history is taken
and symptoms are monitored in addition to
clinical testing, dry eye disease can be controlled.
This is the first in a series of articles on dry eye
disease.
The Dry Eye Treatment Center
Located at
Carolina Forest Family Eyecare
3874 Renee Drive
Myrtle Beach, SC 29579
(843) 903-6262
Root Decay… A Serious Matter
By: Jeffrey W. Horowitz, D.M.D., F.A.G.D.
The general population is steadily aging, and despite
paying more attention to their oral health, one dental
condition persists for adults and continues to increase
in prevalence, root cavities. Root cavities pose an
urgent threat to teeth in that if they are not treated
aggressively; premature loss of the teeth can almost
always be assured. Root cavities are not always obvious
to the patient, and it is not uncommon for a tooth to
have a hopeless prognosis by the time the average person
can visibly see one. Although it is not the most
glamorous of subjects, I wanted to use this month’s
article to explain more about this condition, what the
risk factors are, and preventative measures that can be
taken.
Understanding how and why these cavities develop is
critical in developing a strategy for prevention and
treatment. As the name obviously suggests, root decay
affects the root of the tooth, below the enamel covered
portion that is well protected. Indeed the root has no
enamel, and if looked at microscopically, would appear
quite rough and porous. This is one reason that
bacterial plaque and biofilm are so often found in
abundance there. When left undisturbed by poor oral
hygiene, and fueled by high carbohydrate or acidic
diets, the bacteria produce acids that will readily
penetrate the weak surface, resulting in a root cavity.
With no hard enamel to slow the process down the cavity
spreads like a wild fire, and in little time can break
down a tooth to the level of the nerve or all the way to
the jaw bone. When this happens there is little hope for
saving the tooth.
Risk factors for developing root cavities include
age, poor salivary flow, poor oral hygiene, prior dental
decay and restoration, acidic and high carbohydrate
diets, gum disease and gum recession. What the first
five have in common is that they all revolve around a
low pH (acidic) oral environment. Bacteria that cause
decay flourish in an acidic environment. Our saliva acts
as a natural buffer, neutralizing an environment that
would otherwise be too acidic. Having poor salivary flow
automatically puts one at risk for dental decay.
Unfortunately this is a very common problem for the
elderly, as many medications cause Dry Mouth Syndrome. A
patient on any three or more prescription medications
must be considered at higher risk for dental decay
because of the high likelihood of dry mouth. Be assured
however, that dental decay is not just limited to the
elderly. Acidic diets including regular exposure to
fruit juices and soft drinks can also cause decay.
Additionally, many young people use medications like
diet aids, energy boosters, and antihistamines that
create dry mouth syndrome just as in the elderly
population. Finally, and perhaps most importantly, is
that roots need to be exposed to the bacteria of the
oral environment for a cavity to begin there. This means
that someone with gum disease, prior gum disease or gum
recession must take extra precaution to avoid root
decay.
Prevention of root caries has two primary
strategies. First is preventing root exposure. Although
not all recession is preventable, good oral hygiene and
regular dental care can prevent gum disease and bone
loss, which lead to receding gums and root exposure.
Avoiding excessively hard brushing or a hard bristled
toothbrush can also reduce trauma to the gums that can
cause recession.
Once root exposure does exist, the second strategy
of cavity prevention must be employed. First and
foremost is good oral hygiene, along with a low
carbohydrate, non acidic diet. For those with salivary
impairment, use of sugar free products that promote
saliva flow and contain Xylitol, a non digestible sugar
to the oral bacteria, has been shown to help with caries
prevention. When combined with prescription fluorides
and/or remineralization products available from your
dentist, root caries incidence can be dramatically
reduced. Perhaps one of the most effective methods of
prevention is a root coverage procedure. This can be
achieved with gum grafting or by covering all of the
tooth structure above the gums with a crown. When decay
does not exist, gum grafting is a much more conservative
approach, especially with the advent of new materials
that don’t require harvesting gum tissue from the
patient. These new allograft materials act as
scaffolding for the body to form new tissue around the
root, and have made the procedure applicable for
multiple graft sites. Discomfort from the procedure is
minimal making it more attractive to patients. When
decay exists, or when the tooth has already been
restored, placing a crown to cover the root may be
preferable.
If you suspect root decay or one of the risk
factors, do not waste time visiting your dentist. It
just may make the difference in keeping your teeth!
Dr Horowitz is a 1991 graduate of The Medical
University of South Carolina, College of Dental Medicine
and completed a General practice residency at the
Mountainside Hospital In Montclair, N.J. He is a Fellow
of the Academy of General Dentistry as well as a member
of the American Academy of Cosmetic Dentistry, the
American Orthodontic Society, and The American Dental
Association. He is the owner and dentist at the Carolina
Center for Cosmetic and Restorative Dentistry at 1515
9th Ave., Conway, S.C. He can be contacted at (843)
248-3843 or via the Web at
www.carolinacosmeticdental.com.
I am
over 40, can I wear Contact Lenses?
By Dr. Thomas Weshefsky
I
am over 40, can I wear contact lenses? I hear this
question on a daily basis. The answer is almost always,
YES! You Can Wear Contact Lenses.
Most people in the over-40s crowd are suffering from
discovering that their arms are growing shorter as words
become increasingly more difficult to read up close.
This condition, called presbyopia, occurs as the eye
gradually loses its ability to focus on objects close at
hand causing you to hold small items at arms length.
Initially, this problem may only occur in dim lighting
situations such as in restaurants but over time it will
worsen until it is impossible to read or to carry out
close work at all.
If you are over 40, you're probably much more active
than your parents were at your age. Biking, jogging,
exercising and playing sports are just a few of the
activities that today's Baby Boomers routinely enjoy.
So it's no surprise that many 40-somethings and
older Baby Boomers prefer contact lenses over glasses
for their active lifestyles.
But once we reach our mid-40s,
presbyopia makes it difficult to focus on
near objects. Until recently,
reading glasses were the only option
available to contact lens wearers who wanted to read a
menu or do other everyday tasks that require good near
vision.
But today, a number of multifocal contact lens
options are available for you to consider. Multifocal
contact lenses offer the best of both worlds: no
glasses, along with good near and distance vision.
Some multifocal contact lenses have a bifocal design
with two distinct lens powers — one for your distance
vision and one for near.
Others have a multifocal design somewhat like
progressive eyeglass lenses, with a gradual
change in lens power for a natural visual transition
from distance to closeup.
Multifocal contacts are available in both
soft and oxygen permeable lens materials and
are designed for
daily wear or
extended (overnight) wear. Soft multifocal
lenses can be comfortably worn on a part-time basis, so
they're great for weekends and other occasions if you
prefer not to wear them on an all-day, every day
schedule.
For the ultimate in convenience, one-day disposable
soft multifocal lenses allow you to discard the lenses
at the end of a single day of wear, so there's no hassle
with lens care.
For the ultimate in vision, oxygen permeable
multifocal contact lenses provide sharper visual acuity
than soft multifocals. Another advantage to over-40
people, who are more susceptible than younger people to
dry eye syndrome, is that oxygen permeable
contact lenses don't contain water, and they don't
absorb moisture from your eyes the way soft lenses will.
They also resist collecting bits of protein and other
debris from your tears much better than soft lenses.
It's these deposits that can make soft lenses
uncomfortable and scratchy, especially for dry-eye
sufferers.
This new generation of oxygen permeable multifocal
contact lenses are designed using an instrument called a
Corneal Topographer. This instrument analyses your
cornea and creates a virtual 3D map of the surface of
your eye.
Using computer aided design / computer aided
manufacturing (CAD/CAM) software, we design and create a
lens that is a perfect fit. In essence, we are creating
a virtual mold of your eye which allows us to make a
lens which is as individual to your eye as your
fingerprints are to your hand. Because these lenses are
molded to the shape of your eye, they are exceptionally
comfortable and they give the sharpest vision possible.
With all of the new multifocal contact lens designs
available today, an eye doctor who understands that one
size does not fit all, can help you find the lenses that
work best for you.
You may be over 40 but YES! You Can Wear Contact
Lenses!
Next month, we will discuss how you can get great
vision without glasses, without contact lenses, without
lasers and without risky surgery even if you are over
40!
Dr. Thomas Weshefsky, Carolina Forest Family Eyecare
- 3874 Renee Drive
Myrtle Beach, SC 29579 (843) 903-6262 Dr.W@CarolinaForestEyecare.com
Flip-Flops Tied
to Surge in Teenage Heel Pain
By Dr. Scott Hamilton DPM, FACFAS
Many of us are welcoming the warmer weather sporting
flip-flop sandals; however, their popularity among teens
and young adults is responsible for a growing epidemic
of heel pain in this population, according to Dr. Scott
Hamilton DPM, FACFAS a member of the American College of
Foot and Ankle Surgeons.
“We’re seeing more heel pain than ever in patients
15 to 25 years old, a group that usually doesn’t have
this problem,” says Hamilton. “A major contributor is
wearing flip-flop sandals with paper-thin soles everyday
to school. Flip-flops have no arch support and can
accentuate any abnormal biomechanics in foot motion, and
this eventually brings pain and inflammation.”
Hamilton recommends wearing sandals with reasonably
strong soles and arch support.
“Especially for girls and young women, thicker soled
sandals with supportive arches might not be considered
stylish, but if you want to wear sandals most of the
time, you’ll avoid heel pain if you choose sturdier,
perhaps less fashionable styles,” He says.
It is estimated that 15 percent of all adult foot
complaints involve plantar fasciitis, the type of heel
pain caused by chronic inflammation of the connective
tissue extending from the heel bone to the toes. Being
overweight and wearing inappropriate footwear are common
contributing factors.
The pain is most noticeable after getting out of bed
in the morning, and it tends to decrease after a few
minutes and returns during the day as time on the feet
increases. Not all heel pain, however, is caused by
plantar fasciitis. It also can occur from inflammation
of the Achilles tendon, bursitis, arthritis, gout,
stress fractures, or irritation of one or more of the
nerves in the region. Therefore, diagnosis by a foot and
ankle surgeon to rule out other causes is advised.
Initial treatment options for heel pain caused by
plantar fasciitis should include anti-inflammatory
medications, padding and strapping of the foot and
physical therapy. Patients also should stretch their
calf muscles regularly, avoid wearing flat shoes and
walking barefoot, use over-the-counter arch supports and
heel cushions, and limit the frequency of extended
physical activities.
Most patients with plantar fasciitis respond to
non-surgical treatment within six weeks. However,
surgery is sometimes necessary to relieve severe,
persistent pain.
For further information about heel pain, contact Dr.
Scott Hamitlon at (843) 449-8079, or visit
www.coastalpodiatry.com.
Breast Cancer:
Identification of Gene Mutation Allows Women and
their Physicians to Identify Women Who Are At
Increased Risk for Hereditary Breast & Ovarian
Cancer Syndrome
By: N. Craig Brackett, III, M.D., FACS and Angela
M. Mislowsky, M.D.
Aside from non-melanoma skin cancer, breast cancer
is the most common form of cancer in women, and is
second only to lung cancer, as a cause of cancer
death.
According to the American Cancer Society, about 1.3
million women will be diagnosed with breast cancer
annually worldwide and about 465,000 will die from
the disease.
Breast cancer rates have decreased slightly in
recent years and thanks to early diagnosis we are
finding them at a much earlier stage. The sheer
fact, however, that one in eight American women face
the dreaded disease each year is enough to make them
ask, “What can I do to prevent breast cancer?”
While evidence shows that healthy eating and
regular exercise can contribute to breast
cancer prevention, there are even more risks you
can’t control such as your age and genetic make
up.
Incidence rates increase dramatically with age.
While the current rate of increase in breast cancer
incidence is greatest in women under age 50, the
majority of cases still occur after age 50.
Statistics show that fifty percent of cases are
diagnosed prior to age 64 with the remaining fifty
percent occurring in women 64 and older.
Women of higher socioeconomic status, married women,
women living in urban versus rural areas, and women in
northern states have the highest rates.
Both genetic and environmental factors are believed to
play a role in a woman's risk of developing breast
cancer. If either a woman's mother or sister has
breast cancer, the risk is two or three times as great.
If both a mother and a sister have breast cancer,
the risk is up to five times as great. If that relative
had bilateral breast cancer or was diagnosed at an early
age, the risk may be further increased.
To date, most inherited cases of breast cancer have been
associated with two genes: BRCA1, which stands for BReast
CAncer gene one, and BRCA2, or BReast
CAncer gene two.
The function of these genes is to keep breast cells
growing normally and to prevent any cancer cell growth.
But when these genes contain abnormalities, or
mutations, they are associated with an increased breast
cancer risk. Abnormal BRCA1 and BRCA2 genes may account
for up to 10% of all breast cancers.
Women diagnosed with breast cancer who have an abnormal
BRCA1 or BRCA2 gene often have a family history of
breast cancer, ovarian cancer, or both. But it's also
important to remember that most women with breast cancer
have no family history of the disease.
Identifying BRCA1 and BRCA2 has led to new techniques
for detecting, treating and lowering the risk of breast
cancer. For women who wish to be tested, we can now
establish whether or not the two genes are normal.
It is important to remember, however, that this simple
blood test doesn’t test for, or indicate breast cancer.
It tests for the existence of a BRCA gene mutation which
provides important information in regard to hereditary
risks. Knowing, instead of
wondering, helps many women deal with the risk of breast
cancer. It allows both them and their physicians to
watch more closely for early signs of cancer.
If a woman has a mutated BRCA2 gene, for example,
she has
up
to an 84% chance of breast
cancer by age 70 and up to a 27% chance of developing
ovarian cancer by the same age. It also confers a 12%
risk of a second breast cancer within five years of the
first cancer. BRCA2 also confers a 6% risk of male
breast cancer by age 70 and a 20% risk of prostate
cancer by age 80.
Coastal Carolina Breast Center performs testing to
identify BRCA1 and BRCA2, but reminds women that the
best prevention against breast cancer is early
detection. The Center
offers both screening and diagnostic digital
mammography, breast ultrasound and a special "breast
coil" used in conjunction with the large bore MRI for
specific breast imaging, if needed. Recognized as a
‘Center of Excellence’, Coastal Carolina Breast Center
is the area’s only facility to perform the HALO Breast
Pap Test that may identify breast disease—often a
precursor to cancer—up to eight years earlier than a
lesion might be detected on a traditional mammogram.
Contributing Writers:
Coastal Carolina Breast Center is the area’s only
practice dedicated solely to breast health and is
recognized as a Center of Excellence. Breast specialist,
N. Craig Brackett, III, MD, FACS, joined in practice by
Angela M. Mislowsky, MD, has treated an estimated 25,000
patients during the last fifteen years. Their offices
are located at the Imaging Center at Waccamaw Medical
Park in Murrells Inlet and the Frances B. Ford Cancer
Center in Georgetown, South Carolina. Physician
referrals are not required. For more information or to
make an appointment, call (843) 651-3308 or visit them
on the web at
http://www.coastalbreastcenter.com/
“Hear’s” to YOU!
Can You Afford To Ignore Your Hearing Loss?
By
Dr. Kimberly King,
Board Certified Audiologist
With
the economy and unemployment in its present condition,
it’s time to make known the dramatic link between
hearing loss and earning potential. What are the
financial risks associated with unaddressed hearing
loss?
According to a recent study, people with untreated
hearing loss lose as much as $30,000 in income per year,
depending on their degree of hearing loss. The study
also indicated the cost to society estimated to be as
high as $26 billion in unrealized federal taxes. Yet
people are still under the assumption that they can fake
their way through their work day picking up only partial
conversations and filling in the missing blanks, perhaps
inaccurately.
The risk of income loss was reduced when hearing aids
were utilized as much as 90 to 100 percent for those
with milder hearing loss, and from 65 to 77 percent for
those with severe to moderate hearing loss. It was also
found that there is a strong correlation between degree
of hearing loss and unemployment for those who do not
wear hearing aids. Those with a severe hearing loss
showed unemployment rates (15.6%) double that of the
normal-hearing population (7.8%) and nearly double that
of their peers (8.3%) who use hearing aids. The loss of
income for people with untreated hearing loss due to
underemployment is estimated at $176 billion.
With the U.S. unemployment rates at a steady high and
economic recovery slow, now more than ever, we need to
get out and inform the community of the positive impact
people can have on their own economic circumstances and
quality of life, simply by identifying and appropriately
addressing hearing loss. Treating hearing loss early is
critical for optimal job performance and career
success. And maximizing one’s ability to hear well
should be part of any smart career strategy.
How an employee is perceived by employers is effected by
how he or she hears. Employees who aren’t sure what an
employer is asking can’t answer their best. The ability
to hear and listen well enables employees to be more
productive. They can better understand the work that
has been assigned and the expectations that have been
set. And people who both hear and listen well are more
likely to develop positive working relationships with
bosses, clients, and colleagues.
Unaddressed hearing loss is causing families added
financial strain, and most don’t even realize it. With
the data from this study, “The efficacy of hearing aids
in achieving compensation equity in the workplace,”
(Hearing Journal, October 2010) we’re hoping people will
listen and take action to help themselves. In the end,
hearing better may mean earning more.
If you have concerns regarding your ability to hear,
please contact Advanced Audiology and Hearing Aid
Centers at (843) 663-4327 to schedule an appointment at
one of our three convenient locations in North Myrtle
Beach, Surfside, or Conway.
|